4.3 Non-Coenzyme Functions

This article is currently under construction

Beyond its coenzyme roles, thiamine and its derivatives contribute to:

• Signal modulation – Influencing ion channels and synaptic transmission.

• Oxidative stress protection – Acting as an antioxidant and enhancing glutathione status.

• Neurotransmitter synthesis – Supporting acetylcholine and GABA pathways, influencing cognition and mood.

• Membrane function – Thiamine triphosphate may regulate chloride channels in neurons.