> For the complete documentation index, see [llms.txt](https://www.thiamine.wiki/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://www.thiamine.wiki/thiamine-basics/thiamine-basics/introduction-to-thiamine/4.-biochemistry/4.3-non-coenzyme-functions.md).

# 4.3 Non-Coenzyme Functions

This article is currently under construction

Beyond its coenzyme roles, thiamine and its derivatives contribute to:

* **Signal modulation** – Influencing ion channels and synaptic transmission.
* **Oxidative stress protection** – Acting as an antioxidant and enhancing glutathione status.
* **Neurotransmitter synthesis** – Supporting acetylcholine and GABA pathways, influencing cognition and mood.
* **Membrane function** – Thiamine triphosphate may regulate chloride channels in neurons.